Lolo Jones has some strong (albeit playful) words for Shaquille O'Neal after the NBA legend called Angel Reese LSU's G.O.A.T. ... telling TMZ Sports Diesel had to be "high" when he made the statement.

Jones -- who starred for LSU's track team before competing in BOTH the Summer and Winter Olympics -- got wind of O'Neal referring to Reese as the greatest athlete to ever come out of Baton Rouge on his 'Big Podcast' this week, and she vehemently disagreed with her fellow Tigers alum.

In fact, she seemed to think Shaq wasn't in his right mind since undergoing surgery last month.