Rob Gronkowski will NEVER play another down in the NFL ... at least, that's what the future Hall of Famer is now saying -- telling TMZ Sports this week there's "no chance" he comes back.

The 33-year-old hung up his spikes in June 2022 ... but many thought he could eventually make a return -- considering he had already retired and unretired once before in his career.

But, after sitting out the entire 2022 season -- and, after his good buddy, Tom Brady, called it quits this offseason -- Gronk told Michael Babcock and Mojo Muhtadi he's officially done.

"There's no chance anymore," the former Buccaneers and Patriots tight end said of a possible comeback. "I'm happily retired."